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Gene-expression profiling of prostate tumors

(Submitter supplied) Increasing evidence suggests that prostate cancer is overdiagnosed and overtreated, and prognostic biomarkers would aid in treatment selection. To define prognostic biomarkers for aggressive prostate cancer, we carried out gene-expression profiling of 98 prostate tumors and 52 benign adjacent prostate tissue samples with detailed clinical annotation. We identified 28 transcripts significantly associated with recurrence after radical prostatectomy including NuSAP, a protein that binds DNA to the mitotic spindle. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
4 related Platforms
153 Samples
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Series
Accession:
GSE40272
ID:
200040272

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