IL-2 therapy restores regulatory T cell dysfunction induced by calcineurin inhibitors - - GEO DataSets

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IL-2 therapy restores regulatory T cell dysfunction induced by calcineurin inhibitors

(Submitter supplied) CNIs drastically modify the Treg specific transcriptional program in vivo in an IL-2 dependent manner CD4+CD25+FOXP3+ regulatory T cells (Tregs) constitute a heterogeneous lymphocyte subpopulation essential for establishing peripheral immune tolerance. Interleukin-2 (IL-2) plays a critical role in maintaining immune homeostasis promoting optimal development, survival and function of Tregs. Because of their suppressive properties, manipulation of Tregs represents a clear target to modulate immune responses in transplantation and autoimmunity. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL21798
30 Samples

Download data: CEL

Series

Accession:: GSE80814

ID:: 200080814

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IL-2 therapy restores regulatory T cell dysfunction induced by calcineurin inhib...
IL-2 therapy restores regulatory T cell dysfunction induced by calcineurin inhibitors
Accession: GSE80814

GEO DataSets
GPL21798[RGSE] (1)
GEO DataSets
Echeneis naucrates chromosome 16 genomic scaffold, fEcheNa1.1 16, whole genome s...
Echeneis naucrates chromosome 16 genomic scaffold, fEcheNa1.1 16, whole genome shotgun sequence
gi|1681080771|gnl|ASM:GCF_900963304 |ref|NW_021780158.1||gpp|GPS_018550227.1|

Nucleotide
Echeneis naucrates chromosome 19 genomic scaffold, fEcheNa1.1 19, whole genome s...
Echeneis naucrates chromosome 19 genomic scaffold, fEcheNa1.1 19, whole genome shotgun sequence
gi|1681080768|gnl|ASM:GCF_900963304 |ref|NW_021780161.1||gpp|GPS_018550230.1|

Nucleotide

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