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Items: 9

1.

The effect of BMP4/6 stimulation on adult muscle stem cells (MuSC)

(Submitter supplied) Muscle development and regeneration strongly depends on extracellular cues and growth factors, which are taken up by muscle stem cells and guide them either towards proliferation and fusion or towards quiescence. Here we investigated the effect of bone morphogenetic protein (BMP) signaling on Pax7 positive adult muscle stem cells of the mouse. We discovered a cross talk between the BMP- and NOTCH-signalling pathways, leading to high upregulation upon BMP4/BMP6-stimulation of Hes1 mRNA which is a key component of the NOTCH-siganling pathway.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL26250
6 Samples
Download data: CEL
Series
Accession:
GSE127798
ID:
200127798

Analyze with GEO2R

2.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Mus musculus
143 DataSets
2499 Series
28 Related Platforms
30153 Samples
Download data
Platform
Accession:
GPL6246
ID:
100006246

3.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [CDF: MoGene10stv1_Mm_ENSG v.21.0.0]

(Submitter supplied) This is identical to GPL6246 but a custom cdf environment was used to extract data.
Organism:
Mus musculus
1 Series
1 Related Platform
6 Samples
Download data: CDF, TXT
Platform
Accession:
GPL26250
ID:
100026250

4.

MuSC vehilce treated, biological rep. 3

Organism:
Mus musculus
Source name:
MuSC from mouse #2 treated with vehicle
Platform:
GPL26250
Series:
GSE127798
Download data: CEL
Sample
Accession:
GSM3639091
ID:
303639091

5.

MuSC vehicle treated, biological rep. 2

Organism:
Mus musculus
Source name:
MuSC from mouse #2 treated with vehicle
Platform:
GPL26250
Series:
GSE127798
Download data: CEL
Sample
Accession:
GSM3639090
ID:
303639090

6.

MuSC vehicle treated, biological rep. 1

Organism:
Mus musculus
Source name:
MuSC from mouse #1 treated with vehicle
Platform:
GPL26250
Series:
GSE127798
Download data: CEL
Sample
Accession:
GSM3639089
ID:
303639089

7.

MuSC BMP6 treated, biological rep. 3

Organism:
Mus musculus
Source name:
MuSC from mouse #3 treated with 100 ng/ml BMP6
Platform:
GPL26250
Series:
GSE127798
Download data: CEL
Sample
Accession:
GSM3639088
ID:
303639088

8.

MuSC BMP6 treated, biological rep. 2

Organism:
Mus musculus
Source name:
MuSC from mouse #2 treated with 100 ng/ml BMP6
Platform:
GPL26250
Series:
GSE127798
Download data: CEL
Sample
Accession:
GSM3639087
ID:
303639087

9.

MuSC BMP6 treated, biological rep. 1

Organism:
Mus musculus
Source name:
MuSC from mouse #1 treated with 100 ng/ml BMP6
Platform:
GPL26250
Series:
GSE127798
Download data: CEL
Sample
Accession:
GSM3639086
ID:
303639086

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