GEO DataSets

(Submitter supplied) To evaluate decellularized skeletal muscle extracellular matrix hydrogel effectiveness in treating shoulder cuff tears using a rabbit (RI) model. Male New Zealand white rabbits had supraspinatus tendon severed and were housed for 12 weeks, after which they had tendon reattached and half of rabbits also received an extracellular matrix gel injection. We then performed gene expression profiling analysis using data obtained from RNA-seq from rabbit supraspinatus muscles (n=5 for repair+gel treatment, n=5 for repair only treatment , n=4 for injured control) at 2 weeks post and (n=5 for repair+gel treatment, n=5 for repair only treatment , n=5 for uninjured control) at 12 weeks post treatment

Organism:

Oryctolagus cuniculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28431

34 Samples

Download data: TAB

(Submitter supplied) Brown adipose tissue (BAT) in rabbits undergoes rapid involution, i.e. transforming to white adipose tissue (WAT), similarly to what happens in humans. We aim to profile the transcriptomic changes of total BAT and the stromal vascular fraction (SVF) that contains adipocyte progenitors at the global and single-cell levels.

Organism:

Oryctolagus cuniculus

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL28431 GPL26786

39 Samples

Download data: TXT, XLSX

(Submitter supplied) The availability of viral entry factors is a prerequisite for the cross-species transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Large-scale single-cell screening on animal cells is a powerful tool to reveal the expression patterns of viral entry genes for different hosts. But such exploration for SARS-CoV-2 remained limited. Here, we presented the broadest pan-species single-nucleus RNA sequencing study to date, covering 11 representative species in pets (cat, dog, hamster, lizard), livestock (goat, rabbit), poultry (duck, pigeon) and wildlife (pangolin, tiger, deer), from which we investigated the co-expression of ACE2 and TMPRSS2. more...

Organism:

Capra aegagrus; Manis javanica; Cervus nippon taiouanus; Oryctolagus cuniculus; Mesocricetus auratus; Anas platyrhynchos; Canis lupus familiaris; Anolis carolinensis; Panthera tigris altaica; Columba livia; Felis catus

Type:

Expression profiling by high throughput sequencing

11 related Platforms

29 Samples

Download data: TXT