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Items: 5

1.

Comparative 3D Genome Architecture in Vertebrates

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Gallus gallus; Sus scrofa; Oryctolagus cuniculus; Bos taurus; Ovis aries; Mus musculus; Rattus norvegicus; Danio rerio; Felis catus; Macaca mulatta; Homo sapiens; Canis lupus familiaris
Type:
Expression profiling by high throughput sequencing; Other
12 related Platforms
54 Samples
Download data: BED, HDF5, XLS
Series
Accession:
GSE167581
ID:
200167581
2.

Comparative 3D Genome Architecture in Vertebrates (RNA-Seq)

(Submitter supplied) Three-dimensional genome architecture influences the regulation of essential nuclear processes, such as gene transcription. However, how 3D genome architecture is affected by evolutionary forces within major lineages remains unclear. Here, we report a comprehensive comparison of 3D genomes, using high resolution Hi-C data in fibroblast cells of fish, chickens, and 10 mammalian species. This analysis shows a correlation between genome size and chromosome length that affects chromosomal territory (CT) organization in the upper hierarchy of genome architecture, whereas lower hierarchical features, including local transcriptional availability of DNA, are selected through vertebrate’s evolution. more...
Organism:
Gallus gallus; Sus scrofa; Oryctolagus cuniculus; Mus musculus; Danio rerio; Macaca mulatta; Homo sapiens; Canis lupus familiaris; Felis catus; Bos taurus; Ovis aries; Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
12 related Platforms
29 Samples
Download data: TXT
Series
Accession:
GSE167580
ID:
200167580
3.

Comparative 3D Genome Architecture in Vertebrates (Hi-C)

(Submitter supplied) Three-dimensional genome architecture influences the regulation of essential nuclear processes, such as gene transcription. However, how 3D genome architecture is affected by evolutionary forces within major lineages remains unclear. Here, we report a comprehensive comparison of 3D genomes, using high resolution Hi-C data in fibroblast cells of fish, chickens, and 10 mammalian species. This analysis shows a correlation between genome size and chromosome length that affects chromosomal territory (CT) organization in the upper hierarchy of genome architecture, whereas lower hierarchical features, including local transcriptional availability of DNA, are selected through vertebrate’s evolution. more...
Organism:
Homo sapiens; Mus musculus; Felis catus; Bos taurus; Ovis aries; Oryctolagus cuniculus; Rattus norvegicus; Canis lupus familiaris; Danio rerio; Gallus gallus; Macaca mulatta
Type:
Other
11 related Platforms
25 Samples
Download data: BED, HDF5, XLS
Series
Accession:
GSE167579
ID:
200167579
4.

A Pig BodyMap Transcriptome Reveals Diverse Tissue Physiologies and Evolutionary Dynamics of Transcription

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Sus scrofa; Mus musculus; Gallus gallus; Macaca mulatta; Homo sapiens; Canis lupus familiaris; Cavia porcellus; Felis catus; Ovis aries; Oryctolagus cuniculus; Rattus norvegicus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
19 related Platforms
553 Samples
Download data: HIC, TXT
Series
Accession:
GSE162148
ID:
200162148
5.

A Pig BodyMap Transcriptome Reveals Diverse Tissue Physiologies and Evolutionary Dynamics of Transcription [RNA-Seq across species]

(Submitter supplied) Comprehensive transcriptomic survey of the pig (Sus scrofa) may lead to a better understanding of mechanisms of tissue specialization that underlie economic traits of this species and accelerate its use as a biomedical model. Here, we characterized four distinct transcript types (lncRNAs, TUCPs, miRNAs and circRNAs) in 31 adult pig tissues and two cell lines, together with protein-coding genes. We dissected their distinct structural and transcriptional features and uncovered transcriptome variability as related to tissue physiology. more...
Organism:
Macaca mulatta; Felis catus; Mus musculus; Rattus norvegicus; Gallus gallus; Ovis aries; Oryctolagus cuniculus; Canis lupus familiaris; Cavia porcellus
Type:
Expression profiling by high throughput sequencing
9 related Platforms
142 Samples
Download data: TXT
Series
Accession:
GSE162142
ID:
200162142
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