Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation - - GEO DataSets

Summary

Format

Summary
Summary (text)
Unique Identifier List

Send to:

Choose Destination

File
Clipboard
Collections

Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation

(Submitter supplied) Mammals differ more than 100-fold in maximum lifespan. Here, we conducted comparative transcriptomics on 26 species with diverse lifespans. We identified thousands of genes with expression levels negatively or positively correlated with a species' maximum lifespan (Neg- or Pos-MLS genes). Neg-MLS genes are primarily involved in energy metabolism and inflammation. Pos-MLS genes show enrichment in DNA repair, microtubule organization, and RNA transport. more...

Organism:: Blarina brevicauda; Tamiasciurus hudsonicus; Rattus rattus; Myocastor coypus; Heterocephalus glaber; Castor canadensis; Acomys russatus; Mesocricetus auratus; Mus musculus; Sciurus carolinensis; Tamias striatus; Neotoma cinerea; Condylura cristata; Fukomys damarensis; Peromyscus maniculatus; Ondatra zibethicus; Hydrochoerus hydrochaeris; Ellobius lutescens; Cuniculus paca; Cricetulus barabensis; Marmota monax; Cavia porcellus; Octodon degus; Chinchilla lanigera; Scalopus aquaticus

Type:: Expression profiling by high throughput sequencing

25 related Platforms
522 Samples

Download data: TXT

Series

Accession:: GSE190756

ID:: 200190756

PubMed Full text in PMC Similar studies SRA Run Selector

Supplemental Content

Related information

PubMed
Related PubMed entries
Full text in PMC
PMC links
Similar studies
Similar studies
BioProject
BioProject links
SRA
Links to Short Read Archive Experiments
Taxonomy
Taxonomy

Search details

Important Links

Recent activity

Clear Turn Off Turn On

GPL31067[RGSE] (1)
GEO DataSets
Comparative transcriptomics reveals circadian and pluripotency networks as two p...
Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation
Accession: GSE190756

GEO DataSets
Cincelichthys bocourti cytochrome b gene, partial cds; mitochondrial
Cincelichthys bocourti cytochrome b gene, partial cds; mitochondrial
gi|297660075|gb|GU736984.1|

Nucleotide
NADH dehydrogenase subunit 2, partial (mitochondrion) [Amblysomus corriae]
NADH dehydrogenase subunit 2, partial (mitochondrion) [Amblysomus corriae]
gi|778335073|gb|AJY59265.1|

Protein
cytochrome b, partial (mitochondrion) [Amblysomus hottentotus iris]
cytochrome b, partial (mitochondrion) [Amblysomus hottentotus iris]
gi|969943595|gb|ALU32932.1|

Protein

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on