GEO DataSets

(Submitter supplied) The Sevenless receptor (Sev) is a key component of the complex regulatory network involved in R7 photoreceptor determination. However the genetic program that responds to Sev is still unknown. Here, we explore the transcriptional profile downstream of Sev, using eye imaginal discs from third instar larvae of the sev mutants sevS11 and sevd2 compared with wild-type controls. Keywords: loss and gain of function analysis

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3797

7 Samples

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(Submitter supplied) Upstream of N-ras (UNR) is a conserved RNA-binding protein that regulates mRNA translation and stability by binding to sites generally located in untranslated regions (UTRs). In Drosophila, sex-specific binding of UNR to various RNAs plays key roles in the control of X chromosome dosage compensation in both sexes. In order to investigate broader sex-specific functions of UNR, we have identified its RNA targets in adult male and female flies by high-throughput RNA binding and transcriptome analysis. more...

Organism:

Drosophila melanogaster

Type:

Other

Platform:

GPL3797

6 Samples

Download data: GPR

(Submitter supplied) SAP18 is a highly evolutionarily conserved protein found in all eukaryotic organisms from Saccharomycces cerevisiae to humans. It has been proposed to be involved in multiple cellular processes, from gene regulation to mRNA processing, playing different cellular functions, such as cell fate control during development or regulation of apoptosis or salt stress responses. Previous studies found SAP18 capable of repressing transcription when tethered directly to a promoter region. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3797

4 Samples

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(Submitter supplied) Research on the ability of certain organisms to reconstruct missing structures of their bodies is still in its infancy, despite numerous efforts performed in multiple species. Using expression profile analyses on different timepoints that cover wound healing and regeneration processes (0, 24 and 72 hours post injury), we studied the regenerative behaviour of fragmented wing imaginal discs of D. melanogaster implanted into adult flies. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3797

12 Samples

Download data

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3797

8 Samples

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(Submitter supplied) We have performed a systematic examination of genome-wide expression profiles using microarrays to reconstruct a global picture of the trx regulatory gene network in D. melanogaster. Using computational analysis of the microarray data, we have identified 25 clusters of genes potentially regulated by trx, most of them being located in the arm L of chromosome 3. Functional analysis revealed that most clusters are enriched in structural proteins involved in cuticle formation, which are preferently expressed in salivary glands. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3797

4 Samples

Download data

(Submitter supplied) We have performed a systematic examination of genome-wide expression profiles using microarrays to reconstruct a global picture of the trx regulatory gene network in D. melanogaster. Using computational analysis of the microarray data, we have identified 25 clusters of genes potentially regulated by trx, most of them being located in the arm L of chromosome 3. Functional analysis revealed that most clusters are enriched in structural proteins involved in cuticle formation, which are preferently expressed in salivary glands. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3797

4 Samples

Download data

(Submitter supplied) The absent, small or homeotic discs 2 (ash2) gene, a member of the trithorax Group (trxG) of transcriptional regulators, is functionally related to ash1. However, ASH2 and ASH1 belong to distinct multimeric complexes of unknown composition and it is unclear how they act to regulate transcription. In this study, examination of gene expression profiles in wing imaginal discs from ash2 and ash1 mutants revealed their transcriptomes are very similar and correlate with wing phenotypes. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3797

12 Samples

Download data