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Items: 5

1.

Understanding Bovine Embryo Elongation: A Transcriptomic Study of Trophoblastic Vesicles

(Submitter supplied) Background: During the process of elongation, the embryo increases in size within the uterus while the extra-embryonic tissues (EET) develop and differentiate in preparation for implantation. As it grows, the ovoid embryo changes shape into first a tubular and then a filamentous form. This process is directed by numerous genes and pathways, the expression of which may be altered in the case of developmental irregularities such as when the conceptus is shorter than expected or when the embryo develops after splitting. more...
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL7417
24 Samples
Download data: TXT
Series
Accession:
GSE146768
ID:
200146768
2.

Primary bovine extra-embryonic cultured cells: a new resource for the study of in vivo peri-implanting phenotypes and mesoderm formation

(Submitter supplied) In addition to nourishing the embryo, extra-embryonic tissues (EETs) contribute to early embryonic patterning, primitive hematopoiesis, and fetal health. These tissues are of major importance for human medicine, as well as for efforts to improve livestock efficiency, but they remain incompletely understood. In bovines, EETs are accessible easily, in large amounts, and prior to implantation. We took advantage of this system to describe, in vitro and in vivo, the cell types present in bovine EETs at Day 18 of development. more...
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL7417
14 Samples
Download data: TXT
Series
Accession:
GSE52967
ID:
200052967
3.

The effect of underfeeding on gene expression in the bovine tract during postpartum

(Submitter supplied) This study aimed to investigate the effect of a mild underfeeding on global gene expression in the oviduct, the endometrium and the corpus luteum between 4 and 15 days post-ovulation in postpartum (PP) Holstein cows. Four control cows (C) received 100% of energy and protein requirements after calving when 4 underfed (U) received 80% of the control diet. Oestrus synchronization treatment was applied to induce ovulation on D80 PP. more...
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL7417
24 Samples
Download data: TXT
Series
Accession:
GSE28707
ID:
200028707
4.

Defective uncoupled differentiations after nuclear reprogramming

(Submitter supplied) Somatic cell nuclear transfer (SCNT) is the most efficient cell reprogramming technique available, especially when working with bovine species. Although SCNT blastocysts performed equally well or better than controls in the weeks following embryo transfer at Day 7, elongation and gastrulation defects were observed prior to implantation. To understand the developmental implications of embryonic/extra-embryonic interactions, the morphological and molecular features of elongating and gastrulating tissues were analysed. more...
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL7417
40 Samples
Download data: TXT
Series
Accession:
GSE34944
ID:
200034944
5.

Molecular prediction of gastrulation stages with small extra-embryonic gene-set

(Submitter supplied) Axis specification in mouse is determined by a sequence of reciprocal interactions between embryonic and extra-embryonic tissues so that a few extra-embryonic genes appear as ‘patterning’ the embryo. Considering these interactions as essential, but lacking in most mammals the genetically driven approaches used in mouse and the corresponding patterning mutants, we examined whether a molecular signature originating from extra-embryonic tissues could relate to the developmental stage of the embryo proper and predict it. more...
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL7417
20 Samples
Download data
Series
Accession:
GSE13013
ID:
200013013
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