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1.

The acute effects of methoxyacetic acid exposure on testis gene expression

(Submitter supplied) We evaluated the possible mechanisms by which 2-methoxyacetic acid (MAA) disrupts spermatogenesis using high density microarrays. Levels of mRNA transcripts were determined in total RNA isolated from testes of MAA-treated (650 mg/kg i.p.) or concurrent control rats sacrificed 4, 8, 12 or 24 hrs post exposure (PE). Keywords: Toxicology, Time Course,
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3184
Platform:
GPL890
47 Samples
Download data: TXT
Series
Accession:
GSE10032
ID:
200010032

PubMed Similar studies Analyze with GEO2R

2.
Full record GDS3184

Methoxyacetic acid effect on testis: time course

Analysis of testes of males exposed to methoxyacetic acid (MAA) for up to 24 hours. MAA is an in vivo metabolite of ethylene glycol monomethoxy ether, a solvent in industrial and household applications. Results provide insight into the mechanisms underlying the disruption of spermatogenesis by MAA.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, log2 ratio, 2 agent, 4 time sets
Platform:
GPL890
Series:
GSE10032
47 Samples
Download data: TXT
DataSet
Accession:
GDS3184
ID:
3184

PubMed Similar studies GEO Profiles Analyze DataSet

3.

Agilent-011868 Rat Oligo Microarray G4130A (Feature Number version)

(Submitter supplied) This microarray contains representative sequences derived from rat RefSeq, high-quality public rat mRNA accessions, homologs to human and mouse RefSeq, EST clusters determined by a leading biopharmaceutical company and the Incyte Zooseq database as well as toxicology markers determined by the National Institute of Environmental Health Sciences (NIEHS) and others. Many of the toxicology markers used in the design of this microarray were released to the public domain for the first time and will be used on this unique microarray product. more...
Organism:
Rattus norvegicus
9 DataSets
30 Series
1 Related Platform
1093 Samples
Download data: TXT
Platform
Accession:
GPL890
ID:
100000890

4.

MAA43

Organism:
Rattus norvegicus
Source name:
650 mg methoxyacetic acid/kg body weight_24 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253576
ID:
300253576

5.

MAA40

Organism:
Rattus norvegicus
Source name:
650 mg methoxyacetic acid/kg body weight_24 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253575
ID:
300253575

6.

Con41

Organism:
Rattus norvegicus
Source name:
saline_24 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253574
ID:
300253574

7.

Con38

Organism:
Rattus norvegicus
Source name:
saline_24 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253573
ID:
300253573

8.

MAA28

Organism:
Rattus norvegicus
Source name:
650 mg methoxyacetic acid/kg body weight_12 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253572
ID:
300253572

9.

Con29

Organism:
Rattus norvegicus
Source name:
saline_12 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253571
ID:
300253571

10.

Con26

Organism:
Rattus norvegicus
Source name:
saline_12 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253570
ID:
300253570

11.

Con10

Organism:
Rattus norvegicus
Source name:
saline_4 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253569
ID:
300253569

12.

MAA8

Organism:
Rattus norvegicus
Source name:
650 mg methoxyacetic acid/kg body weight_4 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253568
ID:
300253568

13.

Con42

Organism:
Rattus norvegicus
Source name:
saline_24 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253567
ID:
300253567

14.

Con30

Organism:
Rattus norvegicus
Source name:
saline_12 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253566
ID:
300253566

15.

Con18

Organism:
Rattus norvegicus
Source name:
saline_8 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253565
ID:
300253565

16.

Con6

Organism:
Rattus norvegicus
Source name:
saline_4 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253564
ID:
300253564

17.

MAA31

Organism:
Rattus norvegicus
Source name:
650 mg methoxyacetic acid/kg body weight_12 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253563
ID:
300253563

18.

Con9

Organism:
Rattus norvegicus
Source name:
saline_4 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253562
ID:
300253562

19.

MAA35

Organism:
Rattus norvegicus
Source name:
650 mg methoxyacetic acid/kg body weight_12 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253561
ID:
300253561

20.

MAA32

Organism:
Rattus norvegicus
Source name:
650 mg methoxyacetic acid/kg body weight_12 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)
Platform:
GPL890
Series:
GSE10032
Dataset:
GDS3184
Download data: TXT
Sample
Accession:
GSM253560
ID:
300253560

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