GSE10915[Accession] - GEO DataSets

Select item 2000109151.

Comparative analysis of gene expression in ob/ob leptin-treated and ob/ob saline-treated lungs.

(Submitter supplied) We hypothesize that gene expression in the lungs of these differentially-treated mice are divergent thus contributing to the disparity in their phenotypes. More specifically, (1) Effects of Leptin-treatment of ob/ob postnatal mice lungs are known to be volume-dependent from 2 to 10 wks of age, and are independent of the hypometabolism associated with leptin deficiency. ; (2) Leptin is critical to postnatal lung remodeling, particularly related to enlarged alveolar surface area. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3316
Platform:: GPL339
6 Samples

Download data: CEL

Series

Accession:: GSE10915

ID:: 200010915

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 33162.

Leptin deficiency effect on lungs

Analysis of lungs from leptin-deficient (ob/ob) mutants treated with saline or leptin. Leptin deficiency results in low lung volumes and an attenuated chemical control of breathing. Results provide insight into molecular mechanisms by which leptin alters respiratory system structure and function.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL339
Series:: GSE10915
6 Samples

Download data: CEL

DataSet

Accession:: GDS3316

ID:: 3316

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000003393.

[MOE430A] Affymetrix Mouse Expression 430A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip Mouse Genome 430A 2.0 Array is accessioned in GEO as GPL8321. June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...