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Items: 8

1.

The licorice metabolite enoxolone attenuates Clostridioides difficile pathophysiology by corrupting its metabolic and toxin production networks

(Submitter supplied) Toxins TcdA and TcdB are the main virulence factors of Clostridioides difficile, a leading cause of hospital-acquired diarrhea. We investigated the therapeutic potential of inhibiting the biosynthesis of TcdA and TcdB. Accordingly, screening of structurally diverse phytochemicals with medicinal properties identified 18b-glycyrrhetinic acid (enoxolone) as an inhibitor of TcdA and TcdB biosynthesis. Enoxolone also inhibited sporulation. more...
Organism:
Clostridioides difficile
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30071
6 Samples
Download data: TXT
Series
Accession:
GSE199109
ID:
200199109

2.

Illumina NovaSeq 6000 (Clostridioides difficile)

Organism:
Clostridioides difficile
3 Series
26 Samples
Download data
Platform
Accession:
GPL30071
ID:
100030071

3.

Enoxolone_3

Organism:
Clostridioides difficile
Source name:
Planktonic cells
Platform:
GPL30071
Series:
GSE199109
Download data
Sample
Accession:
GSM5964512
ID:
305964512

SRA Run Selector

4.

Enoxolone_2

Organism:
Clostridioides difficile
Source name:
Planktonic cells
Platform:
GPL30071
Series:
GSE199109
Download data
Sample
Accession:
GSM5964511
ID:
305964511

SRA Run Selector

5.

Enoxolone_1

Organism:
Clostridioides difficile
Source name:
Planktonic cells
Platform:
GPL30071
Series:
GSE199109
Download data
Sample
Accession:
GSM5964510
ID:
305964510

SRA Run Selector

6.

DMSO_3

Organism:
Clostridioides difficile
Source name:
Planktonic cells
Platform:
GPL30071
Series:
GSE199109
Download data
Sample
Accession:
GSM5964509
ID:
305964509

SRA Run Selector

7.

DMSO_2

Organism:
Clostridioides difficile
Source name:
Planktonic cells
Platform:
GPL30071
Series:
GSE199109
Download data
Sample
Accession:
GSM5964508
ID:
305964508

SRA Run Selector

8.

DMSO_1

Organism:
Clostridioides difficile
Source name:
Planktonic cells
Platform:
GPL30071
Series:
GSE199109
Download data
Sample
Accession:
GSM5964507
ID:
305964507

SRA Run Selector

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db=gds|term=GSE199109[Accession]|query=1|qty=2|blobid=MCID_6675d0dbccfbad768fa7dd29|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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