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Items: 14

1.

Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma

(Submitter supplied) Metabolic reprogramming is critical during clear cell renal cell carcinoma (ccRCC) tumorigenesis, manifested by accumulation of lipid droplets (LDs), organelles that have emerged as new hallmarks of cancer. Yet, regulation of their biogenesis is still poorly understood. Here, we demonstrate that MYC inhibition in ccRCC cells lacking the von Hippel Lindau (VHL) gene leads to increased triglyceride content potentiating LD formation in a glutamine-dependent manner. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30173
12 Samples
Download data: TXT
Series
Accession:
GSE223069
ID:
200223069

PubMed Full text in PMC Similar studies

2.

NextSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
852 Series
15886 Samples
Download data
Platform
Accession:
GPL30173
ID:
100030173

3.

RCC4 VHL+  JQ1 R3

Organism:
Homo sapiens
Source name:
RCC4 VHL + JQ1
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939184
ID:
306939184

SRA Run Selector

4.

RCC4 VHL+ DMSO R3

Organism:
Homo sapiens
Source name:
RCC4 VHL + DMSO
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939183
ID:
306939183

SRA Run Selector

5.

RCC4 VHL-  JQ1 R3

Organism:
Homo sapiens
Source name:
RCC4 VHL -  JQ1
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939182
ID:
306939182

SRA Run Selector

6.

RCC4 VHL-  DMSO R3

Organism:
Homo sapiens
Source name:
RCC4 VHL -  DMSO
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939181
ID:
306939181

SRA Run Selector

7.

RCC4 VHL+  JQ1 R2

Organism:
Homo sapiens
Source name:
RCC4 VHL +  JQ1
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939180
ID:
306939180

SRA Run Selector

8.

RCC4 VHL+ DMSO R2

Organism:
Homo sapiens
Source name:
RCC4 VHL +  DMSO
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939179
ID:
306939179

SRA Run Selector

9.

RCC4 VHL-  JQ1 R2

Organism:
Homo sapiens
Source name:
RCC4 VHL -  JQ1
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939178
ID:
306939178

SRA Run Selector

10.

RCC4 VHL-  DMSO R2

Organism:
Homo sapiens
Source name:
RCC4 VHL -  DMSO
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939177
ID:
306939177

SRA Run Selector

11.

RCC4 VHL-  JQ1 R1

Organism:
Homo sapiens
Source name:
RCC4 VHL -  JQ1
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939175
ID:
306939175

SRA Run Selector

12.

RCC4 VHL-  DMSO R1

Organism:
Homo sapiens
Source name:
RCC4 VHL -  DMSO
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939174
ID:
306939174

SRA Run Selector

13.

RCC4 VHL+  JQ1 R1

Organism:
Homo sapiens
Source name:
RCC4 VHL +  JQ1
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939173
ID:
306939173

SRA Run Selector

14.

RCC4 VHL+ DMSO R1

Organism:
Homo sapiens
Source name:
RCC4 VHL + DMSO
Platform:
GPL30173
Series:
GSE223069
Download data
Sample
Accession:
GSM6939171
ID:
306939171

SRA Run Selector

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