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Items: 8

1.

Activation of the PARIS immune complex by viral proteins results in host tRNA cleavage and can be overcome by viruses encoding non-cleavable tRNAs

(Submitter supplied) Viruses compete with other viruses for limited cellular recourses, and some viruses deliver defense mechanisms that protect the host from competing genetic parasites. PARIS is a defense system, often encoded in viral genomes, that is composed of a 53 kDa ABC ATPase (AriA) and a 35 kDa TOPRIM nuclease (AriB). Here we show that AriA and AriB assemble into a 425 kDa supramolecular immune complex. We use cryo-EM to determine the structure of this complex which explains how six molecules of AriA assemble into a propeller-shaped scaffold that coordinates three subunits of AriB. more...
Organism:
Escherichia coli
Type:
Other
Platform:
GPL21222
6 Samples
Download data: COOL
Series
Accession:
GSE270519
ID:
200270519
2.

Illumina NextSeq 500 (Escherichia coli)

Organism:
Escherichia coli
127 Series
2301 Samples
Download data
Platform
Accession:
GPL21222
ID:
100021222
3.

Hi-C of E.coli :MG1655 + cm 20 µg/ml Contrôle (30min)

Organism:
Escherichia coli
Source name:
MG1655
Platform:
GPL21222
Series:
GSE270519
Download data: COOL
Sample
Accession:
GSM8346099
ID:
308346099
4.

Hi-C of E.coli :MG1655 + cm 20 µg/ml Contrôle (15min)

Organism:
Escherichia coli
Source name:
MG1655
Platform:
GPL21222
Series:
GSE270519
Download data: COOL
Sample
Accession:
GSM8346098
ID:
308346098
5.

Hi-C of E.coli :MG1655 + DPAG 50 uM (30 min) Paris

Organism:
Escherichia coli
Source name:
MG1655
Platform:
GPL21222
Series:
GSE270519
Download data: COOL
Sample
Accession:
GSM8346097
ID:
308346097
6.

Hi-C of E.coli :MG1655 + DPAG 50 uM (15min) Paris

Organism:
Escherichia coli
Source name:
MG1655
Platform:
GPL21222
Series:
GSE270519
Download data: COOL
Sample
Accession:
GSM8346096
ID:
308346096
7.

Hi-C of E.coli :MG1655 + DPAG 50 uM (30 min) WT

Organism:
Escherichia coli
Source name:
MG1655
Platform:
GPL21222
Series:
GSE270519
Download data: COOL
Sample
Accession:
GSM8346095
ID:
308346095
8.

Hi-C of E.coli: MG1655 + DPAG 50 uM (15 min) WT

Organism:
Escherichia coli
Source name:
MG1655
Platform:
GPL21222
Series:
GSE270519
Download data: COOL
Sample
Accession:
GSM8346094
ID:
308346094
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Supplemental Content

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