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Items: 1 to 20 of 70

1.

TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis–induced immune tolerance

(Submitter supplied) Severe and chronic infections, including pneumonia, sepsis, and tuberculosis (TB), induce long-lasting epigenetic changes that are associated with an increase in all cause post-infectious morbidity and mortality. We show that TCA cycle also regulates epigenetics, specifically DNA methylation, after infection induced immune tolerance. This data from TB patients who received everolimus with standard of care antibiotics, and have less DNA hypermethylation demonstrating proof of concept that metabolic manipulation can mitigate epigenetic scars.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL21145
68 Samples
Download data: IDAT, XLS
Series
Accession:
GSE277003
ID:
200277003

PubMed Similar studies

2.

Infinium MethylationEPIC

(Submitter supplied) See manufacturer's website
Organism:
Homo sapiens
1168 Series
1 Related Platform
79858 Samples
Download data: CSV
Platform
Accession:
GPL21145
ID:
100021145

3.

D68 [502-0152-5]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511749
ID:
308511749

4.

D67 [550-0070-7]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511748
ID:
308511748

5.

D66 [550-0069-5]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511747
ID:
308511747

6.

D65 [550-0064-0]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511746
ID:
308511746

7.

D64 [502-0121-1]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511745
ID:
308511745

8.

D63 [502-0088-3]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511744
ID:
308511744

9.

D62 [502-0082-7]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511743
ID:
308511743

10.

D61 [551-0039-3]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511742
ID:
308511742

11.

D60 [551-0041-6]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511741
ID:
308511741

12.

D59 [550-0029-1]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511740
ID:
308511740

13.

D58 [502-0036-6]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511739
ID:
308511739

14.

D57 [551-0014-6]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511738
ID:
308511738

15.

D56 [550-0009-9]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511737
ID:
308511737

16.

D55 [502-0163-7]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511736
ID:
308511736

17.

D54 [550-0058-3]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511735
ID:
308511735

18.

D53 [502-0118-7]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511734
ID:
308511734

19.

D52 [551-0029-2]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511733
ID:
308511733

20.

D51 [502-0059-1]

Organism:
Homo sapiens
Source name:
Peripheral Blood Mononuclear cell
Platform:
GPL21145
Series:
GSE277003
Download data: IDAT
Sample
Accession:
GSM8511732
ID:
308511732

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