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Items: 17

1.

Post-therapeutic relapse of psoriasis associated with CD11a blockade is associated with T cells and inflammatory myeloid DCs

(Submitter supplied) To understand the development of new psoriasis lesions, we studied a group of moderate-to-severe psoriasis patients who experienced a relapse after ceasing efalizumab (anti-CD11a, Raptiva, Genentech). There were increased CD3+ T cells, neutrophils, CD11c+ and CD83+ myeloid DCs, but no increase in CD1c+ resident myeloid DCs. In relapsed lesions, there were many CD11c+CD1c-, inflammatory myeloid DCs identified by TNFSF10/TRAIL, TNF, and iNOS. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4606
Platform:
GPL571
14 Samples
Download data: CEL
Series
Accession:
GSE30768
ID:
200030768
2.
Full record GDS4606

Post-therapeutic relapse of psoriasis: whole skin punch biopsies

Analysis of skin samples from 4 responding patients who relapsed following efalizumab treatment for psoriasis: baseline non-lesional and lesional samples; week 12 post-treatment and relapse samples. Results provide insight into molecular mechanisms underlying post-therapeutic relapse of psoriasis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 disease state, 4 individual, 2 time sets
Platform:
GPL571
Series:
GSE30768
14 Samples
Download data: CEL
3.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
641 Series
12 Related Platforms
24467 Samples
Download data
Platform
Accession:
GPL571
ID:
100000571
4.

Patient P4 @LS

Organism:
Homo sapiens
Source name:
Patient P4 @LS
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763515
ID:
300763515
5.

Patient P2 @LS

Organism:
Homo sapiens
Source name:
Patient P2 @LS
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763514
ID:
300763514
6.

Patient P4 @Week 12

Organism:
Homo sapiens
Source name:
Patient P4 @Week 12
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763513
ID:
300763513
7.

Patient P1 @LS

Organism:
Homo sapiens
Source name:
Patient P1 @LS
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763512
ID:
300763512
8.

Patient P2 @FLARE

Organism:
Homo sapiens
Source name:
Patient P2 @FLARE
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763511
ID:
300763511
9.

Patient P3 @LS

Organism:
Homo sapiens
Source name:
Patient P3 @LS
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763510
ID:
300763510
10.

Patient P4 @FLARE

Organism:
Homo sapiens
Source name:
Patient P4 @FLARE
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763509
ID:
300763509
11.

Patient P1 @NL

Organism:
Homo sapiens
Source name:
Patient P1 @NL
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763508
ID:
300763508
12.

Patient P1 @FLARE

Organism:
Homo sapiens
Source name:
Patient P1 @FLARE
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763507
ID:
300763507
13.

Patient P1 @Week 12

Organism:
Homo sapiens
Source name:
Patient P1 @Week 12
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763506
ID:
300763506
14.

Patient P3 @FLARE

Organism:
Homo sapiens
Source name:
Patient P3 @FLARE
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763505
ID:
300763505
15.

Patient P2 @Week 12

Organism:
Homo sapiens
Source name:
Patient P2 @Week 12
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763504
ID:
300763504
16.

Patient P4 @NL

Organism:
Homo sapiens
Source name:
Patient P4 @NL
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763503
ID:
300763503
17.

Patient P3 @Week 12

Organism:
Homo sapiens
Source name:
Patient P3 @Week 12
Platform:
GPL571
Series:
GSE30768
Dataset:
GDS4606
Download data: CEL
Sample
Accession:
GSM763502
ID:
300763502
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Supplemental Content

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