GEO DataSets

(Submitter supplied) Cohesin is crucial for proper chromosome segregation, but also regulates gene transcription and organism development by poorly understood mechanisms. We find that in Drosophila, cohesin functionally interacts with Polycomb group (PcG) silencing proteins at both silenced and active genes. Cohesin unexpectedly facilitates binding of Polycomb Repressive Complex 1 (PRC1) to many active genes. In contrast, cohesin and PRC1 binding are mutually antagonistic at silenced genes. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

9 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 06, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Drosophila Genome 2.0 Array is a microarray tool for studying expression of Drosophila melanogaster transcripts: - Provides comprehensive coverage of the transcribed Drosophila genome on a single array - Comprised of 18,880 probe sets, analyzing over 18,500 transcripts Sequences used in the design of the GeneChip Drosophila Genome 2.0 Array were selected from Flybase version 3.1. more...

Organism:

Drosophila melanogaster

25 DataSets

362 Series

1 Related Platform

5224 Samples

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