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Items: 14

1.

Addiction of t(8;21) and inv(16) AML to native RUNX1 [ChIP-Seq data]

(Submitter supplied) Cancer cells maintain a sensitive balance between growth-promoting oncogenes and apoptosis inhibitors. We show that WT RUNX1 is required for survival of t(8;21)-Kasumi-1 and inv(16)-ME-1 AML cell lines. The malignant AML phenotype is sustained by a delicate AML1-ETO/RUNX1 balance that involves competition for common DNA binding sites regulating a subset of AML1-ETO/RUNX1 targets.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL10999
12 Samples
Download data: BW
Series
Accession:
GSE45738
ID:
200045738

PubMed Similar studies SRA Run Selector

2.

Illumina Genome Analyzer IIx (Homo sapiens)

Organism:
Homo sapiens
1103 Series
10072 Samples
Download data
Platform
Accession:
GPL10999
ID:
100010999

3.

Kasumi_RUNX1_N_TERMINUS_2

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113438
ID:
301113438

SRA Run Selector

4.

Kasumi_RUNX1_N_TERMINUS_1

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113437
ID:
301113437

SRA Run Selector

5.

Kasumi_AP4_NIS2

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113436
ID:
301113436

SRA Run Selector

6.

Kasumi_AP4_NIS1

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113435
ID:
301113435

SRA Run Selector

7.

Kasumi_AP4_2

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113434
ID:
301113434

SRA Run Selector

8.

Kasumi_AP4_1

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113433
ID:
301113433

SRA Run Selector

9.

Kasumi_RUNX1_NIS_2

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113432
ID:
301113432

SRA Run Selector

10.

Kasumi_RUNX1_NIS_1

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113431
ID:
301113431

SRA Run Selector

11.

Kasumi_AML1_ETO_2

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113430
ID:
301113430

SRA Run Selector

12.

Kasumi_AML1_ETO_1

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113429
ID:
301113429

SRA Run Selector

13.

Kasumi_RUNX1_2

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113428
ID:
301113428

SRA Run Selector

14.

Kasumi_RUNX1_1

Organism:
Homo sapiens
Source name:
Kasumi-1 cell culture
Platform:
GPL10999
Series:
GSE45738 GSE45748
Download data: BW
Sample
Accession:
GSM1113427
ID:
301113427

SRA Run Selector

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