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Items: 8

1.

Scl specifies hemogenic endothelium and inhibits cardiogenesis via primed enhancers [expression]

(Submitter supplied) Scl/Tal1 confers hemogenic competence and prevents cardiomyogenesis in embryonic endothelium. Here we show that Scl both directly activates a broad gene regulatory network required for hematopoietic stem/progenitor cell (HS/PC) development, and represses transcriptional regulators required for cardiogenesis. Cardiac repression occurs during a short developmental window through Scl binding to distant cardiac enhancers that harbor H3K4me1 at this stage. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
6 Samples
Download data: CEL
Series
Accession:
GSE47084
ID:
200047084
2.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4546 Series
40 Related Platforms
58941 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
3.

SclKO_Flk+Scl-_rep2

Organism:
Mus musculus
Source name:
SclKO_Flk+Scl-
Platform:
GPL1261
Series:
GSE47084 GSE47085
Download data: CEL
Sample
Accession:
GSM1144565
ID:
301144565
4.

SclKO_Flk+Scl-_rep1

Organism:
Mus musculus
Source name:
SclKO_Flk+Scl-
Platform:
GPL1261
Series:
GSE47084 GSE47085
Download data: CEL
Sample
Accession:
GSM1144564
ID:
301144564
5.

WT_Flk+Scl-_rep2

Organism:
Mus musculus
Source name:
WT_Flk+Scl-
Platform:
GPL1261
Series:
GSE47084 GSE47085
Download data: CEL
Sample
Accession:
GSM1144563
ID:
301144563
6.

WT_Flk+Scl-_rep1

Organism:
Mus musculus
Source name:
WT_Flk+Scl-
Platform:
GPL1261
Series:
GSE47084 GSE47085
Download data: CEL
Sample
Accession:
GSM1144562
ID:
301144562
7.

WT_Flk+Scl+_rep2

Organism:
Mus musculus
Source name:
WT_Flk+Scl+
Platform:
GPL1261
Series:
GSE47084 GSE47085
Download data: CEL
Sample
Accession:
GSM1144561
ID:
301144561
8.

WT_Flk+Scl+_rep1

Organism:
Mus musculus
Source name:
WT_Flk+Scl+
Platform:
GPL1261
Series:
GSE47084 GSE47085
Download data: CEL
Sample
Accession:
GSM1144560
ID:
301144560
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Supplemental Content

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