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Items: 15

1.

GRHL1 acts as a tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3

(Submitter supplied) Neuroblastoma is an embryonic solid tumor of neural crest origin and accounts for 11% of all cancer-related deaths in children. Novel therapeutic strategies are therefore urgently required. MYCN oncogene amplification, which occurs in 20% of neuroblastomas, is a hallmark of high risk. Here we aimed to exploit molecular mechanisms that can be pharmacologically addressed with epigenetically modifying drugs, such as histone deacetylase (HDAC) inhibitors. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5263
Platform:
GPL10558
12 Samples
Download data: TXT
Series
Accession:
GSE47407
ID:
200047407
2.
Full record GDS5263

Enforced Grainyhead-like 1 expression effect on BE(2)-C neuroblastoma cell line: time course

Analysis of BE(2)-C cells up to 72 hrs after transient transfection with construct pTRex-GRHL1. The three mammalian GRHL genes (GRHL1, -2, and -3) represent a highly conserved family of β-scaffold transcription factors. Results provide insight into the role of GRHL1 in neuroblastoma biology.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol, 3 time sets
Platform:
GPL10558
Series:
GSE47407
12 Samples
Download data
DataSet
Accession:
GDS5263
ID:
5263
3.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...
Organism:
Homo sapiens
51 DataSets
2943 Series
4 Related Platforms
104956 Samples
Download data: TXT
Platform
Accession:
GPL10558
ID:
100010558
4.

GRHL1 72h rep2

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149047
ID:
301149047
5.

empty vector 72h rep2

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149046
ID:
301149046
6.

GRHL1 72h rep1

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149045
ID:
301149045
7.

empty vector 72h rep1

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149044
ID:
301149044
8.

GRHL1 48h rep2

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149043
ID:
301149043
9.

empty vector 48h rep2

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149042
ID:
301149042
10.

GRHL1 48h rep1

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149041
ID:
301149041
11.

empty vector 48h rep1

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149040
ID:
301149040
12.

GRHL1 24h rep2

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149039
ID:
301149039
13.

empty vector 24h rep2

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149038
ID:
301149038
14.

GRHL1 24h rep1

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149037
ID:
301149037
15.

empty vector 24h rep1

Organism:
Homo sapiens
Source name:
BE(2)-C cell line
Platform:
GPL10558
Series:
GSE47407
Dataset:
GDS5263
Download data
Sample
Accession:
GSM1149036
ID:
301149036
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Supplemental Content

db=gds|term=GSE47407[Accession]|query=14|qty=2|blobid=MCID_6733dce35c1af073747bc2c0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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    Hadrosciurus sp. 3 EFA-2022 tRNA-Phe, 12S ribosomal RNA, tRNA-Val, 16S ribosomal RNA, and tRNA-Leu genes, complete sequence; NADH dehydrogenase subunit 1 (ND1) gene, complete cds; tRNA-Ile, tRNA-Gln, and tRNA-Met genes, complete sequence; NADH dehydrogenase subunit 2 (ND2) gene, complete cds; tRNA-Trp, tRNA-Ala, tRNA-Asn, tRNA-Cys, and tRNA-Tyr genes, complete sequence; cytochrome c oxidase subunit I (COX1) gene, complete cds; tRNA-Ser and tRNA-Asp genes, complete sequence; cytochrome c oxidase subunit II (COX2) gene, complete cds; tRNA-Lys gene, complete sequence; ATP synthase F0 subunit 8 (ATP8), ATP synthase F0 subunit 6 (ATP6), and cytochrome c oxidase subunit III (COX3) genes, complete cds; tRNA-Gly gene, complete sequence; NADH dehydrogenase subunit 3 (ND3) gene, complete cds; tRNA-Arg gene, complete sequence; NADH dehydrogenase subunit 4L (ND4L) and NADH dehydrogenase subunit 4 (ND4) genes, complete cds; tRNA-His, tRNA-Ser, and tRNA-Leu genes, complete sequence; NADH dehydrogenase subunit 5 (ND5) and NADH dehydrogenase subunit 6 (ND6) genes, complete cds; tRNA-Glu gene, complete sequence; cytochrome b (CYTB) gene, complete cds; and tRNA-Thr and tRNA-Pro genes and D-loop, complete sequence; mitochondrial.
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