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Items: 14

1.

Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis

(Submitter supplied) The platelet-derived growth factor receptor alpha (PDGFRα) exhibits divergent effects in skeletal muscle. At physiological levels, signaling through this receptor promotes muscle development in growing embryos and proper angiogenesis in regenerating adult muscle. However, either increased PDGF ligands or enhanced PDGFRα pathway activity causes pathological fibrosis. This excessive collagen deposition, which is seen in aged and diseased muscle, interferes with proper muscle function and limits the effectiveness of gene- and cell-based therapies for muscle disorders. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
12 Samples
Download data: CEL, CHP
Series
Accession:
GSE60099
ID:
200060099

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Mus musculus
143 DataSets
2504 Series
28 Related Platforms
30419 Samples
Download data
Platform
Accession:
GPL6246
ID:
100006246

3.

FAPs_5'ss_AMO_PDGF_50_rep2

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with 5'ss AMO and 50uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464947
ID:
301464947

4.

FAPs_5'ss_AMO_PDGF_50_rep1

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with 5'ss AMO and 50uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464946
ID:
301464946

5.

FAPs_pA_AMO_PDGF_50_rep2

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with pA AMOs and 50uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464945
ID:
301464945

6.

FAPs_pA_AMO_PDGF_50_rep1

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with pA AMOs and 50uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464944
ID:
301464944

7.

FAPs_Cntrl_AMO_PDGF_50_rep2

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with control AMO and 50uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464943
ID:
301464943

8.

FAPs_Cntrl_AMO_PDGF_50_rep1

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with control AMO and 50uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464942
ID:
301464942

9.

FAPs_5'ss_AMO_PDGF_0_rep2

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with 5'ss AMO and 0uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464941
ID:
301464941

10.

FAPs_5'ss_AMO_PDGF_0_rep1

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with 5'ss AMO and 0uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464940
ID:
301464940

11.

FAPs_pA_AMO_PDGF_0_rep2

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with pA AMOs and 0uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464939
ID:
301464939

12.

FAPs_pA_AMO_PDGF_0_rep1

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with pA AMOs and 0uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464938
ID:
301464938

13.

FAPs_Cntrl_AMO_PDGF_0_rep2

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with control AMO and 0uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464937
ID:
301464937

14.

FAPs_Cntrl_AMO_PDGF_0_rep1

Organism:
Mus musculus
Source name:
Fibro/adipogenic progenitors isolated from hindlimb skeletal muscles, treated with control AMO and 0uM PDGF-AA
Platform:
GPL6246
Series:
GSE60099
Download data: CEL, CHP
Sample
Accession:
GSM1464936
ID:
301464936

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