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Items: 6

1.

Manganese (II) Activates cGAS-STING pathway

(Submitter supplied) We show that Manganese (II) is a potent type I-IFN inducing agonist, stimulating cells into an anti-viral state in the absence of infection. Mechanically, Mn2+ treatment led to a profound cGAS-STING-dependent innate immune activation, conferring cells or mice viral resistance.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
4 Samples
Download data: TXT
Series
Accession:
GSE77216
ID:
200077216
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

IFNβ

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE77216
Download data: TXT
Sample
Accession:
GSM2046120
ID:
302046120
4.

VACV

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE77216
Download data: TXT
Sample
Accession:
GSM2046119
ID:
302046119
5.

Mn

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE77216
Download data: TXT
Sample
Accession:
GSM2046118
ID:
302046118
6.

Control

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE77216
Download data: TXT
Sample
Accession:
GSM2046117
ID:
302046117
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Supplemental Content

db=gds|term=GSE77216[Accession]|query=24|qty=2|blobid=MCID_6724196bb9e6a62f8e6e6270|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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