GEO DataSets

(Submitter supplied) Skeletal muscle is a major site of postprandial glucose disposal. Inadequate insulin action in this tissue contributes to hyperglycemia in type 1 and type 2 diabetes. While glucose is known to stimulate insulin secretion by pancreatic b cells, whether it directly engages nutrient-sensing pathways in skeletal muscle to regulate glucose metabolism remains largely unexplored. Here we identified the Baf60c-Deptor-AKT pathway as a target of muscle glucose sensing that augments insulin action in skeletal myocytes. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL17400

8 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html MoGene-2_1-st-v1.na33.2.mm10.transcript.csv #%create_date=Thu Mar 28 17:33:46 2013 PDT #%chip_type=MoGene-2_1-st-v1 #%lib_set_name=MoGene-2_1-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm10 #%genome-version-ucsc=mm10 #%genome-version-ncbi=38 #%genome-version-create_date=2011-12-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm10 #%genome-lifted_from-version-ncbi=38 #%netaffx-annotation-date=2012-09-30 #%netaffx-annotation-netaffx-build=33 Protocol: see manufacturer's web site

Organism:

Mus musculus

214 Series

6 Related Platforms

3551 Samples

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