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Items: 17

1.

A comparative analysis of 5-azacytidine and zebularine induced DNA demethylation using whole-genome bisulfite sequencing

(Submitter supplied) The non-methylable cytosine analogs, 5-azacytidine and zebularine, are widely used to disrupt DNA methyltransferase activity and reduce genomic DNA methylation. In this study, whole-genome bisulfite sequencing is used to construct maps of DNA methylation with single base pair resolution in Arabidopsis thaliana seedlings treated with each demethylating agent. We find that 5-azacytidine and zebularine-treated seedlings have nearly indistinguishable patterns of DNA methylation genome-wide and that 5-azacytidine, despite being more unstable in aqueous solution, has a slightly greater demethylating effect at higher concentrations across the genome. more...
Organism:
Arabidopsis thaliana
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platform:
GPL19580
15 Samples
Download data: DIFF, TSV
Series
Accession:
GSE80300
ID:
200080300
2.

Illumina NextSeq 500 (Arabidopsis thaliana)

Organism:
Arabidopsis thaliana
400 Series
9124 Samples
Download data
Platform
Accession:
GPL19580
ID:
100019580
3.

100µM_AZA-treated_3

Organism:
Arabidopsis thaliana
Source name:
100µM AZA-treated 3
Platform:
GPL19580
Series:
GSE80300
Download data
Sample
Accession:
GSM2124009
ID:
302124009
4.

100µM_AZA-treated_2

Organism:
Arabidopsis thaliana
Source name:
100µM AZA-treated 2
Platform:
GPL19580
Series:
GSE80300
Download data
Sample
Accession:
GSM2124008
ID:
302124008
5.

100µM_AZA-treated_1

Organism:
Arabidopsis thaliana
Source name:
100µM AZA-treated 1
Platform:
GPL19580
Series:
GSE80300
Download data
Sample
Accession:
GSM2124007
ID:
302124007
6.

Mock_treated_4

Organism:
Arabidopsis thaliana
Source name:
Mock treated 4
Platform:
GPL19580
Series:
GSE80300
Download data
Sample
Accession:
GSM2124006
ID:
302124006
7.

Mock_treated_3

Organism:
Arabidopsis thaliana
Source name:
Mock treated 3
Platform:
GPL19580
Series:
GSE80300
Download data
Sample
Accession:
GSM2124005
ID:
302124005
8.

Mock_treated_2

Organism:
Arabidopsis thaliana
Source name:
Mock treated 2
Platform:
GPL19580
Series:
GSE80300
Download data
Sample
Accession:
GSM2124004
ID:
302124004
9.

Mock_treated_1

Organism:
Arabidopsis thaliana
Source name:
Mock treated 1
Platform:
GPL19580
Series:
GSE80300
Download data
Sample
Accession:
GSM2124003
ID:
302124003
10.

ZEB_100

Organism:
Arabidopsis thaliana
Source name:
ZEB 100
Platform:
GPL19580
Series:
GSE80300
Download data: TSV
Sample
Accession:
GSM2124002
ID:
302124002
11.

ZEB_50

Organism:
Arabidopsis thaliana
Source name:
ZEB 50
Platform:
GPL19580
Series:
GSE80300
Download data: TSV
Sample
Accession:
GSM2124001
ID:
302124001
12.

ZEB_25

Organism:
Arabidopsis thaliana
Source name:
ZEB 25
Platform:
GPL19580
Series:
GSE80300
Download data: TSV
Sample
Accession:
GSM2124000
ID:
302124000
13.

AZA_100

Organism:
Arabidopsis thaliana
Source name:
AZA 100
Platform:
GPL19580
Series:
GSE80300
Download data: TSV
Sample
Accession:
GSM2123999
ID:
302123999
14.

AZA_50

Organism:
Arabidopsis thaliana
Source name:
AZA 50
Platform:
GPL19580
Series:
GSE80300
Download data: TSV
Sample
Accession:
GSM2123998
ID:
302123998
15.

AZA_25

Organism:
Arabidopsis thaliana
Source name:
AZA 25
Platform:
GPL19580
Series:
GSE80300
Download data: TSV
Sample
Accession:
GSM2123997
ID:
302123997
16.

Mock_control

Organism:
Arabidopsis thaliana
Source name:
Mock control
Platform:
GPL19580
Series:
GSE80300
Download data: TSV
Sample
Accession:
GSM2123996
ID:
302123996
17.

Untreated_control

Organism:
Arabidopsis thaliana
Source name:
Untreated control
Platform:
GPL19580
Series:
GSE80300
Download data: TSV
Sample
Accession:
GSM2123995
ID:
302123995
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Supplemental Content

db=gds|term=GSE80300[Accession]|query=7|qty=2|blobid=MCID_672eb0a15300667000637034|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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