GSM1074343[Accession] - GEO DataSets

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Items: 3

Select item 2000439151.

In embryo analysis of H3K27 trimethylation suggests a two-step process involving PRC2 interacting sequences and high GC content

(Submitter supplied) ABSTRACT Polycomb group (PcG) proteins are essential for the repression of key developmental regulators during development. In Drosophila, the polycomb repressive complexes (PRC) associate with defined DNA sequences termed polycomb response elements (PREs). In mammals, however, the mechanisms underlying polycomb recruitment at targeted loci are poorly understood. We have used an in vivo approach to try and map DNA sequences of importance for the proper recruitment of polycomb proteins within the genetically well-characterized HoxD genomic locus. more...

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL14183
41 Samples

Download data: BAR, CEL

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Accession:: GSE43915

ID:: 200043915

Select item 1000141832.

Mus musculus HoxD cluster tiling PRNFGMm2b520462F

(Submitter supplied) Oligonucleotide tiling arrays manufactured using photolithography contain probes mapping to a 2 Mb region around the HoxD cluster. Probes corresponding to repetitive or low complexity sequences located within the region were excluded from the array. The arrays are based on NCBI build 36 of the mouse genome (mm8) and contained a total of 75,097 25-mer oligonucleotides (PM and MM) positioned every 15 bp mapping to the reverse strand of chr2: 73,709,305-75,470,233 and 6,323 probes (PM and MM) mapping to the forward strand of chr2: 74,453,853-74, 565,969.