GSM1088313[Accession] - GEO DataSets

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Items: 4

Select item 2000446441.

Dnmt3L-dependent regulation of DNA methylation promotes stem cells differentiation toward primitive germinal cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Methylation profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL6887 GPL16173
14 Samples

Download data: BED

Series

Accession:: GSE44644

ID:: 200044644

Select item 2000446432.

Dnmt3L-dependent regulation of DNA methylation promotes stem cells differentiation toward primitive germinal cells [Expression array]

(Submitter supplied) The de novo DNA methyltransferase 3-like (Dnmt3L) is a catalytically inactive DNA methylase that has been previously shown to cooperate with Dnmt3a and Dnmt3b to methylate DNA. Dnmt3L is highly expressed in mouse embryonic stem cells (ESC) but its function in these cells is unknown. We here report that Dnmt3L is required for the differentiation of ESC into primordial germ cells (PGC) through activation of the homeotic gene Rhox5. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6887
8 Samples

Download data: TXT

Series

Accession:: GSE44643

ID:: 200044643

Select item 1000068873.

Illumina MouseWG-6 v2.0 expression beadchip

(Submitter supplied) The MouseWG-6 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...