GEO DataSets

(Submitter supplied) We have designed a zebrafish genomic microarray to identify DNA-protein interactions in the proximal promoter regions of over 11,000 zebrafish genes. Using these microarrays, together with chromatin immunoprecipitation with an antibody directed against tri-methylated lysine 4 of Histone H3, we demonstrate the feasibility of this method in zebrafish. This approach will allow investigators to determine the genomic binding locations of DNA interacting proteins during development and expedite the assembly of the genetic networks that regulate embryogenesis. more...

Organism:

Danio rerio

Type:

Genome binding/occupancy profiling by genome tiling array

Platforms:

GPL3767 GPL3766

6 Samples

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(Submitter supplied) Microarrays were designed as described below and manufactured by Agilent Technologies (www.agilent.com). Further information on design can be found at http://jura.wi.mit.edu/bioc/gbell/zfish_chip/. The Whitehead zebrafish promoter chipsets were designed for large-scale chromatin immunoprecipitation using microarrays (ChIP chips). The chipsets represent the promoters of about 11,000 transcriptional units derived using transcript sequences from Refseq, Ensembl, Vega, ZGC, and the Zon Lab. more...

Organism:

Danio rerio

1 Series

3 Samples

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