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Items: 4

1.

Genome-wide chromatin maps of T-cell acute lymphoblastic leukemia (T-ALL)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL570 GPL11154
36 Samples
Download data: BW, CEL
Series
Accession:
GSE54380
ID:
200054380
2.

Gene expression profiles of T-cell acute lymphoblastic leukemia cell lines with and without chronic GSI-treatment

(Submitter supplied) Here we modeled T-ALL resistance to Notch inhibition, identifying ‘persister’ cells that readily expand in the presence of gamma secretase inhibitor (GSI) and the absence of Notch signaling. Rare persister cells are already present in naïve T-ALL populations, and the reversibility of the phenotype is suggestive of an epigenetic mechanism. Relative to GSI-sensitive cells, persisters activate distinct signaling and gene expression programs, and exhibit global chromatin compaction. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
8 Samples
Download data: CEL
Series
Accession:
GSE54378
ID:
200054378
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5669 Series
61 Related Platforms
174579 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

Gene expression in KOPT-K1 persister, rep2

Organism:
Homo sapiens
Source name:
KOPT-K1 persister cells
Platform:
GPL570
Series:
GSE54378 GSE54380
Download data: CEL
Sample
Accession:
GSM1314116
ID:
301314116
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