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Items: 4

1.

Therapeutic potential of spleen tyrosine kinase inhibition for treatment of high-risk precursor B-cell acute lymphoblastic leukemia

(Submitter supplied) This study revealed pathogenic role of pre-BCR-independent SYK activation in high-risk B-ALL. Intensified and central nervous system (CNS)-directed chemotherapy has significantly improved outcomes for pediatric B-acute lymphoblastic leukemia (B-ALL), but confers significant late-effect morbidities. Moreover, many patients suffer relapses, underscoring the need to develop novel, molecularly targeted B-ALL therapies. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5640
Platform:
GPL1261
9 Samples
Download data: CEL, CHP
Series
Accession:
GSE56345
ID:
200056345

PubMed Similar studies Analyze with GEO2R

2.
Full record GDS5640

Double-knockout p53/PRKDC model of B cell acute lymphoblastic leukemia: leukemic blasts

Analysis of leukemic blasts from p53/Prkdc double-knockout mutants that spontaneously develop early B cell acute lymphoblastic leukemia (B-ALL). Results provide insight into molecular mechanisms underlying high-risk B-ALL.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE56345
9 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5640
ID:
5640

PubMed Similar studies GEO Profiles Analyze DataSet

3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4546 Series
40 Related Platforms
58941 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261

4.

wt_mouse_proBcells_cultured_1

Organism:
Mus musculus
Source name:
wild type pro-B cells
Platform:
GPL1261
Series:
GSE56345
Dataset:
GDS5640
Download data: CEL, CHP
Sample
Accession:
GSM1359555
ID:
301359555

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db=gds|term=GSM1359555[Accession]|query=5|qty=2|blobid=MCID_67247332bcee590f9736d6f5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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