GEO DataSets

(Submitter supplied) Chronic infection of the human stomach with Helicobacter pylori leads to a variety of pathologic sequelae including peptic ulcer and gastric cancer, resulting in significant human morbidity and mortality. Several genes have been implicated in disease related to H. pylori infection including the vacuolating cytotoxin and the cag pathogenicity island. Other factors important for establishment and maintenance of infection include urease enzyme production, motility, iron uptake and stress response. more...

Organism:

Helicobacter pylori

Type:

Genome variation profiling by array

Platforms:

GPL15 GPL2781

454 Samples

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(Submitter supplied) Microarray Tracking of transposon mutants for a H. pylori mouse colonization screen described in Baldwin DN et al. Screen in NSH57 H. pylori strain background. Original 50,000 clone transposon library was plated and patched to make 25 pools of 48 clones. Clones were infected into 4-8 C57Bl/6 mice and stomach bacteria from at least two mice were harvested at 1 week or one month. Semi-random PCR was used to amplify and label the DNA next to the transposon insertion from the input (Cy3) and output pool (Cy5) genomic DNA for each array. more...

Organism:

Helicobacter pylori

Type:

Genome variation profiling by array

Platform:

GPL2781

194 Samples

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(Submitter supplied) Material is transferred from microtiter plate wells to the slide surface by an automated print head

Organism:

Helicobacter pylori

5 Series

481 Samples

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