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Items: 4

1.

Differentiation of acute myeloid leukemia cells

(Submitter supplied) We developed a general approach to small molecule library screening called GE-HTS (Gene Expression-Based High Throughput Screening) in which a gene expression signature is used as a surrogate for cellular states and applied it to the identification of compounds inducing the differentiation of acute myeloid leukemia cells. In screening 1,739 compounds, we identified 8 that reliably induced the differentiation signature, and furthermore yielded functional evidence of bona fide differentiation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL96 GPL80
117 Samples
Download data: CEL
Series
Accession:
GSE995
ID:
200000995
2.

Gene Expression-Based High Throughput Screening: HL-60 Cell Treatment with Candidate Compounds

(Submitter supplied) We developed a general approach to small molecule library screening called GE-HTS (Gene Expression-Based High Throughput Screening) in which a gene expression signature is used as a surrogate for cellular states and applied it to the identification of compounds inducing the differentiation of acute myeloid leukemia cells. In screening 1,739 compounds, we prioritized 15 candidate compounds (2 were already confirmed in the literature). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
75 Samples
Download data: CEL
Series
Accession:
GSE982
ID:
200000982
3.

[HG-U133A] Affymetrix Human Genome U133A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...
Organism:
Homo sapiens
364 DataSets
1125 Series
11 Related Platforms
42429 Samples
Download data
Platform
Accession:
GPL96
ID:
100000096
4.

AML7

Organism:
Homo sapiens
Source name:
primary patient AML cells
Platform:
GPL96
Series:
GSE982 GSE995
Download data: CEL
Sample
Accession:
GSM15611
ID:
300015611
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