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Items: 3

1.

LTR-retrotransposon control by tRNA-derived small RNA

(Submitter supplied) Transposon reactivation is an inherent danger in cells that lose epigenetic silencing during developmental reprogramming. In the mouse, LTR-retrotransposons, or endogenous retroviruses (ERV), account for most novel insertions and are expressed in the absence of histone H3 Lysine 9 trimethylation in preimplantation stem cells. We found abundant, 18 nt tRNA-derived small RNA (tRF) in these cells, and ubiquitously expressed 22 nt tRFs, that include the 3' terminal CCA of mature tRNAs, and target the tRNA primer binding site (PBS) essential for ERV reverse transcription. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
4 related Platforms
54 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE82199
ID:
200082199

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
10211 Series
294635 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

3.

ES_Dnmt1ko_rep4

Organism:
Mus musculus
Source name:
embryonic stem cell, Dnmt1 knockout
Platform:
GPL19057
Series:
GSE82199
Download data: TXT
Sample
Accession:
GSM2186384
ID:
302186384

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db=gds|term=GSM2186384[Accession]|query=12|qty=3|blobid=MCID_6714d43484112c3be25daea1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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