GSM2344823[Accession] - GEO DataSets

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Items: 3

Select item 2000887261.

Aberrant striatal but not nigral gene expression profiles are specifically associated with dyskinesia behavior following levodopa treatment in the 6-hydroxydopamine lesioned rat

(Submitter supplied) Levodopa-induced dyskinesia (LID) is a common consequence of prolonged pharmacotherapy for Parkinson's disease (PD). While LID becomes more common with long term exposure to levodopa, its development can be quite variable. We leveraged the variable expression of LID in a rat model to interrogate differential gene expression in the substantia nigra and striatum of animals that develop LID and those that do not. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL10741
24 Samples

Download data: CEL

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Accession:: GSE88726

ID:: 200088726

Analyze with GEO2R

Select item 1000107412.

[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [probe set (exon) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html #%create_date=Tue Dec 8 17:34:30 2009 PST #%chip_type=RaGene-1_0-st-v1 #%lib_set_name=RaGene-1_0-st #%lib_set_version=v1 #%genome-species=Rattus norvegicus #%genome-version=rn4 #%genome-version-ucsc=rn4 #%genome-version-ncbi=HGSC v3.4 #%genome-version-create_date=2004-11 #%netaffx-annotation-date=2009-11-16 #%netaffx-annotation-netaffx-build=30.1 Protocol: See manufacturer's web site