GSM2396874[Accession] - GEO DataSets

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Items: 4

Select item 2000900721.

lncRNA dependencies in acute myeloid leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; synthetic construct

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL13112 GPL17769 GPL17021
145 Samples

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Accession:: GSE90072

ID:: 200090072

PubMed Full text in PMC Similar studies

Select item 2000900652.

shRNA screen identifies lncRNAs required for acute myeloid leukemia progresion

(Submitter supplied) It is well understood how proteins regulate cell fate, both in normal development and disease. However, a substantial fraction of the genome is transcribed in a cell type- specific manner, producing long non-coding RNAs (lncRNA) rather than protein- coding transcripts. Here we systematically characterize transcriptional dynamics (both mRNA and lncRNA) during hematopoiesis and in hematological malignancies. more...