GEO DataSets

(Submitter supplied) We present here a genome-wide map of abnormalities found in diagnostic samples from 45 adults and adolescents with acute lymphoblastic leukemia (ALL). 500K single nucleotide polymorphism (SNP) array analysis uncovered frequent genetic abnormalities, with cryptic deletions constituting half of the detected changes, implying that microdeletions are a characteristic feature of this malignancy. Importantly, the pattern of deletions resembled that recently reported in pediatric ALL, suggesting that adult, adolescent, and childhood cases may be more similar on the genetic level than previously thought. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by SNP array; SNP genotyping by SNP array

Platforms:

GPL3720 GPL2641 GPL3718

165 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html As with the previous-generation GeneChip® Mapping 10K Array, the GeneChip Mapping 10K 2.0 Array enables researchers to genotype more than 10,000 SNPs in a single experiment with one primer. The GeneChip Mapping 10K 2.0 Array contains equivalent content and performance as the original GeneChip Mapping 10K Array, but advances in photolithographic technology enable it to be produced in a smaller, more cost-efficient format. more...

Organism:

Homo sapiens

24 Series

8218 Samples

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