GSM253541[Accession] - GEO DataSets

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Items: 4

Select item 2000100321.

The acute effects of methoxyacetic acid exposure on testis gene expression

(Submitter supplied) We evaluated the possible mechanisms by which 2-methoxyacetic acid (MAA) disrupts spermatogenesis using high density microarrays. Levels of mRNA transcripts were determined in total RNA isolated from testes of MAA-treated (650 mg/kg i.p.) or concurrent control rats sacrificed 4, 8, 12 or 24 hrs post exposure (PE). Keywords: Toxicology, Time Course,

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS3184
Platform:: GPL890
47 Samples

Download data: TXT

Series

Accession:: GSE10032

ID:: 200010032

Select item 31842.

Methoxyacetic acid effect on testis: time course

Analysis of testes of males exposed to methoxyacetic acid (MAA) for up to 24 hours. MAA is an in vivo metabolite of ethylene glycol monomethoxy ether, a solvent in industrial and household applications. Results provide insight into the mechanisms underlying the disruption of spermatogenesis by MAA.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, log2 ratio, 2 agent, 4 time sets

Platform:: GPL890
Series:: GSE10032
47 Samples

Download data: TXT

DataSet

Accession:: GDS3184

ID:: 3184

Select item 1000008903.

Agilent-011868 Rat Oligo Microarray G4130A (Feature Number version)

(Submitter supplied) This microarray contains representative sequences derived from rat RefSeq, high-quality public rat mRNA accessions, homologs to human and mouse RefSeq, EST clusters determined by a leading biopharmaceutical company and the Incyte Zooseq database as well as toxicology markers determined by the National Institute of Environmental Health Sciences (NIEHS) and others. Many of the toxicology markers used in the design of this microarray were released to the public domain for the first time and will be used on this unique microarray product. more...

Organism:: Rattus norvegicus

9 DataSets
30 Series
1 Related Platform
1093 Samples

Download data: TXT

Platform

Accession:: GPL890

ID:: 100000890

Select item 3002535414.

MAA11

Organism:: Rattus norvegicus

Source name:: 650 mg methoxyacetic acid/kg body weight_4 hr (channel 1) universal rat reference total RNA (Catalog #740200; Stratagene, La Jolla, CA, USA) (channel 2)