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Items: 3

1.

Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity

(Submitter supplied) To study the function of this residue independent from the enzymes that modify it, we used a “histone replacement” system in Drosophila to generate a non-modifiable H3K36 lysine-to-arginine (H3K36R) mutant. Post-translational modification of histone H3K36 is neither required to suppress cryptic transcription initiation nor to include alternative exons in Drosophila; instead it promotes expression of active genes by stimulating polyadenylation.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL19132 GPL16479 GPL13304
52 Samples
Download data: BED, BW, DIFF
Series
Accession:
GSE96922
ID:
200096922
2.

Illumina HiSeq 2000 (Drosophila melanogaster)

Organism:
Drosophila melanogaster
906 Series
18306 Samples
Download data
Platform
Accession:
GPL13304
ID:
100013304
3.

K36R Nuclear RNA-seq male repB

Organism:
Drosophila melanogaster
Source name:
Whole 3rd Instar Larvae
Platform:
GPL13304
Series:
GSE96922
Download data
Sample
Accession:
GSM2545918
ID:
302545918
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Supplemental Content

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