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Items: 4

1.

Systematic functional characterization of BAF mutations yields novel intra-complex synthetic lethalities

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
162 Samples
Download data
Series
Accession:
GSE108390
ID:
200108390
2.

Systematic functional characterization of BAF mutations yields novel intra-complex synthetic lethalities [RNA-Seq]

(Submitter supplied) Aberrations in genes coding for subunits of the BAF chromatin remodeling complex are highly abundant in human cancers. Currently, it is not understood how these loss-of-function mutations contribute to cancer development and how they can be targeted therapeutically. The cancer type specific occurrence patterns of certain subunit mutations suggest subunit-specific effects on BAF complex function, possibly by the formation of aberrant residual complexes. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
87 Samples
Download data: CSV
3.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
4.

RNA-seq_HAP1_BCL7A_r3_2434_10

Organism:
Homo sapiens
Source name:
HAP1 cell line
Platform:
GPL20301
Series:
GSE108388 GSE108390
Download data
Sample
Accession:
GSM2897216
ID:
302897216
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Supplemental Content

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