GSM307953[Accession] - GEO DataSets

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Items: 4

Select item 2000150131.

Expression of HOXB genes is significantly different in acute myeloid leukemia with a partial tandem duplication of MLL vs. a MLL translocation: a cross-laboratory study

(Submitter supplied) In acute myeloid leukemia (AML), the mixed lineage leukemia (MLL) gene may be rearranged to generate a partial tandem duplication (PTD), or fused to partner genes through a chromosomal translocation (tMLL). In this study, we first explored the differentially expressed genes between MLL-PTD and tMLL using gene expression profiling of our cohort (15 MLL-PTD and 10 tMLL) and one published data set. The top 250 probes were chosen from each set, resulting in 29 common probes (21 unique genes) to both sets. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4277
Platform:: GPL570
25 Samples

Download data: CEL, CHP

Series

Accession:: GSE15013

ID:: 200015013

Select item 42772.

Mixed lineage leukemia gene rearrangements in acute myeloid leukemia: bone marrow mononuclear cells

Analysis of bone marrow cells from AML cases representing MLL chromosomal translocation (tMLL) or partial tandem duplication (MLL-PTD). Rearrangements of MLL at chromosome 11q23 are commonly involved in acute leukemia. Results provide insight into molecular heterogeneity between MLL-PTD and tMLL.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL570
Series:: GSE15013
25 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4277

ID:: 4277

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...