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Items: 4

1.

Initial host response to mycobacterial infection is orchestrated through H3K4 methylation-mediated RNA polymerase II binding at key immune function genes.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bos taurus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL23295 GPL19172
30 Samples
Download data: BW, TXT
Series
Accession:
GSE116734
ID:
200116734
2.

Initial  host  response to mycobacterial infection is orchestrated through H3K4 methylation-mediated RNA polymerase II binding at key immune function genes [RNA-seq]

(Submitter supplied) Massive reprogramming of the host alveolar macrophage transcriptome occurs during the initial stages of tuberculosis. In bovine tuberculosis, Mcobacterium bovis can persist and replicate within alveolar macrophages through varied mechanisms to subvert or exploit host immune responses ( REF). To determine how these transcriptional changes are regulated we performed ChIPseq analysis of H3K4 and H3K27 methylation, established histone tail markers associated with permissive and repressive chromatin states, respectively. more...
Organism:
Bos taurus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23295
8 Samples
Download data: TXT
Series
Accession:
GSE116732
ID:
200116732
3.

Illumina HiSeq 4000 (Bos taurus)

Platform
Accession:
GPL23295
ID:
100023295
4.

Cminus

Organism:
Bos taurus
Source name:
Control_Bovinealveolarmacrophages
Platform:
GPL23295
Series:
GSE116732 GSE116734
Download data: TXT
Sample
Accession:
GSM3259602
ID:
303259602
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