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Items: 3

1.

Differential gene expression in leukemic blasts and leukemic stem cells (LSC) sorted from pediatric AML patients compared to control myeloblasts and hematopoietic stem cells (HSC) sorted from cord blood

(Submitter supplied) Purpose: Currently, only few reports address the molecular abnormalities of LSC compared to HSC in pedAML. Identifying LSC aberrations is crucial to tackle the high relapse rate and to develop therapeutic targeting strategies for LSC elimination, while ensuring salvage of normal HSCs. Methods: Blasts and stem cells were separated based on CD38 expression (positive and negative, respectively). Leukemic blasts (n=4), LSCs (n=3) and lymphocytes (n=4) were sorted from 4 de novo pedAML patients (two FLT3-ITD, two FLT3 WT). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL18641
15 Samples
Download data: TXT
Series
Accession:
GSE128103
ID:
200128103

Analyze with GEO2R

2.

Agilent-050524 CMGG Human V2.0 60k

(Submitter supplied) SurePrint
Organism:
Homo sapiens
6 Series
109 Samples
Download data
Platform
Accession:
GPL18641
ID:
100018641

3.

pedAML 3 blast (K16/2216)

Organism:
Homo sapiens
Source name:
patient pediatric AML
Platform:
GPL18641
Series:
GSE128103
Download data: TXT
Sample
Accession:
GSM3664955
ID:
303664955

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