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Items: 3

1.

Gene expression profiles of mono- and biallelic CEBPA mutations in cytogenetically normal AML

(Submitter supplied) Purpose: CEBPA mutations are found as either biallelic (biCEBPA) or monoallelic (moCEBPA). We set out to explore whether the kind of CEBPA mutation is of prognostic relevance in cytogenetically normal AML (CN-AML). Patients and Methods: 467 homogeneously treated CN-AML patients were subdivided into moCEBPA, biCEBPA and wildtype (wt) CEBPA patients. The subgroups were analyzed for clinical parameters and for additional mutations in the NPM1, FLT3 and MLL genes. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL8289
61 Samples
Download data: CEL
Series
Accession:
GSE15210
ID:
200015210
2.

Affymetrix GeneChip Human Genome U133 Array Set HG-U133A based on a custom CDF (GeneAnnot version 1.4.5)

(Submitter supplied) Affymetrix HG-U133A microarrays analysed with custom chip definition files based on the GeneAnnot database. For further information, see Ferrari F, Bortoluzzi S, Coppe A, Sirota A, Safran M, Shmoish M, Ferrari S, Lancet D, Danieli GA, Bicciato S.: Novel definition files for human GeneChips based on GeneAnnot. BMC Bioinformatics. 2007 Nov 15;8(1):446 We used Version 1.4.5 of custom CDF files and R packages based on GeneAnnot version 1.7 and GeneCards version 2.38, available online at http://www.xlab.unimo.it/GA_CDF/ Protocol: see manufacturer's web site
Organism:
Homo sapiens
1 Series
61 Samples
Download data: CDF
Platform
Accession:
GPL8289
ID:
100008289
3.

CN_AML Patient 4: Wildtype CEBPA

Organism:
Homo sapiens
Source name:
bone marrow mononuclear cells: AML, normal karyotype
Platform:
GPL8289
Series:
GSE15210
Download data: CEL
Sample
Accession:
GSM379878
ID:
300379878
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