GSM384928[Accession] - GEO DataSets

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Items: 3

Select item 2000153321.

Proteomics and transcriptomics analysis of rat retinal ganglion cells exposed to chronic ocular hypertension.

(Submitter supplied) In this work, we tested feasibility of high content screening of acutely isolated RGCs to generate systems biology knowledge of intrinsic cellular pathways associated with the onset of glaucomatous RGC loss in the retina. We performed differential profiling of these neurons using two complementary techniques: proteomics and microarray-based transcriptomics. The analysis of these RGC-specific proteomic and transcriptomic data using pathway informatics databases and biological network tools have revealed complex metabolic and regulatory changes in the COH-challenged neurons. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL4135
8 Samples

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Accession:: GSE15332

ID:: 200015332

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Select item 1000041352.

Agilent-014879 Whole Rat Genome Microarray 4x44K G4131F (Feature Number version)

(Submitter supplied) With a focus on well known rat genes and homologues to human and mouse genes with useful annotation, Agilent's Whole Rat Genome Oligo – 4X44K microarray provides researchers with a new tool for modeling human biology in the rat model organism. For researchers, this means they now have access to a microarray made up of relevant content that has been empirically validated by Agilent. Arrays of this design have barcodes that begin with 16014879 or 2514879. more...