GSM3969787[Accession] - GEO DataSets

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Items: 3

Select item 2001347921.

Molecular and immunological interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild type infection

(Submitter supplied) Enterotoxigenic Escherichia coli (ETEC) infections are a common cause of diarrheal illness in low- and middle-income countries. The live-attenuated ACE527 vaccine, adjuvanted with double mutant LT (dmLT), affords clear but partial protection against ETEC challenge inhuman volunteers. Comparatively, initial wild-type ETEC challenge completely protects against severe diarrhea on homologous re-challenge...To investigate molecular determinants of protection, vaccine antigen content was compared to wild-type ETEC, and proteome microarrays were used to assess immune responses following vaccination and ETEC challenge... more...

Organism:: Homo sapiens; Escherichia coli

Type:: Protein profiling by protein array

Platform:: GPL26932
250 Samples

Download data: XLSX

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Accession:: GSE134792

ID:: 200134792

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000269322.

Antigen Discovery Inc. ETEC Protein Array

(Submitter supplied) Enterotoxigenic Escherichia coli (ETEC); spotted protein - printed without purification from E. coli cell free expression system Protocol: https://antigendiscovery.com/adi-proteome-microarray-technology/