(Submitter supplied) The goal of this study was to understand the mechanisms of miRNA regulation of the transcriptome of tissue engineered cartilage in response to IL-1β and TNF-α using an in vitro murine induced pluripotent stem cell (miPSC) model system. miPSCs were chondrogenically differentiated for 21 days and then treated with 1 ng/mL of IL-1β, 20 ng/mL of TNF-α, or control media without cytokines for 0, 4, 12, 24, and 72 hours.
more...- Organism:
- Mus musculus
- Type:
- Expression profiling by high throughput sequencing; Other
- Platform:
- GPL21493
- 78 Samples
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