GSM4552709[Accession] - GEO DataSets

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Items: 4

Select item 2001506101.

Gene expression profile of primary CLL cells transduced with a mutated NOTCH1

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL16791 GPL24676 GPL20301
82 Samples

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Series

Accession:: GSE150610

ID:: 200150610

PubMed Full text in PMC Similar studies

Select item 2001505842.

Gene expression profile of primary CLL cells transduced with a retrovirus expressing mutated NOTCH1

(Submitter supplied) In CLL, NOTCH1 is the most commonly mutated gene at diagnosis and it is associated with a poor outcome. The mechanisms underlying how NOTCH1 contributes to disease progression, resistance to treatment and Richter’s transformation remain largely unknown. The main goal of this study is to compare the gene expression profile of primary CLL cells transduced with the intracellular part of NOTCH1 lacking of the PEST domain vs cells transduced with an empty vector. more...