GSM4859264[Accession] - GEO DataSets

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Items: 4

Select item 2001600501.

The embryonic ontogeny of the gonadal somatic cells in mice and monkeys

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Macaca fascicularis

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL22523 GPL19057
156 Samples

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Series

Accession:: GSE160050

ID:: 200160050

PubMed Similar studies

Select item 2001600492.

The embryonic ontogeny of the gonadal somatic cells in mice and monkeys [sc3seq]

(Submitter supplied) In the early fetal stage, the gonads are bipotent and only later become the ovary or testis, depending on the genetic sex. Despite many studies examining how sex determination occurs from biopotential gonads, the spatial and temporal organization of bipotential gonads and their progenitors is poorly understood. Here, using lineage tracing in mice, we find that the gonads originate from a T+ primitive streak through WT1+ posterior intermediate mesoderm and appear to share origins anteriorly with the adrenal glands and posteriorly with the metanephric mesenchyme. more...