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Items: 3

1.

Airway administration of flagellin regulates the inflammatory response to Pseudomonas aeruginosa

(Submitter supplied) Here, we aim to understand the role of P38 in the airway epithelial cells response to flagellin. We report the gene expression profile of pig airway epithelial cells cultured under air-liquid conditions, pre-incubated or not with the P38 inhibitor SB203580 (20 µM, Tocris Bioscience) for 1 h and then stimulated with 100 ng/ml of a mutated flagellin (FliCΔ174-400) for 2h or 24h. Our data show that flagellin stimulation induce the expression of pro-inflammatory cytokines mainly through the NFkB pathway, with little impact of P38 inhibition in the cells response.
Organism:
Sus scrofa
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20983
24 Samples
Download data: TXT
Series
Accession:
GSE173768
ID:
200173768
2.

Illumina NextSeq 500 (Sus scrofa)

Platform
Accession:
GPL20983
ID:
100020983
3.

ALI_SB_Flagellin_24h_4

Organism:
Sus scrofa
Source name:
Pig bronchial epithelial cells
Platform:
GPL20983
Series:
GSE173768
Download data
Sample
Accession:
GSM5277962
ID:
305277962
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