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Items: 4

1.

Zygotic genome activation by the totipotency pioneer factor Nr5a2

(Submitter supplied) Life begins with a switch in genetic control from the maternal to the embryonic genome during zygotic genome activation (ZGA). Despite its importance, the essential regulators of ZGA remain largely unknown in mammals. Based on de novo motif searches, we identified the orphan nuclear receptor Nr5a2 as a key activator of major ZGA in mouse 2-cell embryos. Nr5a2 is required for progression beyond the 2-cell stage. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL19057
398 Samples
Download data
Series
Accession:
GSE178661
ID:
200178661
2.

Zygotic genome activation by the totipotency pioneer factor Nr5a2 II

(Submitter supplied) Life begins with a switch in genetic control from the maternal to the embryonic genome during zygotic genome activation (ZGA). Despite its importance, the essential regulators of ZGA remain largely unknown in mammals. Based on de novo motif searches, we identified the orphan nuclear receptor Nr5a2 as a key activator of major ZGA in mouse 2-cell embryos. Nr5a2 is required for progression beyond the 2-cell stage. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
111 Samples
Download data: CSV
Series
Accession:
GSE178654
ID:
200178654
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

Single 2 cell embryo Exp3 C88 15

Organism:
Mus musculus
Source name:
single embryo
Platform:
GPL19057
Series:
GSE178654 GSE178661
Download data
Sample
Accession:
GSM5395349
ID:
305395349
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Supplemental Content

db=gds|term=GSM5395349[Accession]|query=1|qty=2|blobid=MCID_667becee8c5d4760e23ed459|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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