GSM5703779[Accession] - GEO DataSets

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Items: 4

Select item 2001895591.

The study of nascent RNA transcripts in asynchronous cells and cells released from mitosis at the indicated timepoints between Smarce1- MD (R42A) and Smarce1- MD mESCs.

(Submitter supplied) SMARCE1 binding on mitotic chromatin is required for the timely reinitiation of expression of SMARCE1-bookmarked genes and maintaining identity memory in cell division.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24247
48 Samples

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Accession:: GSE189559

ID:: 200189559

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001895632.

Mitotic bookmarking by SWI/SNF subunits

(Submitter supplied) For cells to initiate and sustain a differentiated state, it is necessary that a “memory” of this state is transmitted through mitosis to the daughter cells. Mammalian SWItch/ Sucrose Non- Fermentable (SWI/SNF) complexes, also called Brg1/ Brg- associated factors (BAF), control cell identity by modulating chromatin architecture to regulate gene expression, but whether they participate in cell fate memory is unclear. more...