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Items: 3

1.

Genetic perturbation of AMP biosynthesis extends lifespan and restores metabolic health in a naturally short-lived vertebrate

(Submitter supplied) During aging, the loss of metabolic homeostasis drives a myriad of pathologies. A central regulator of cellular energy, the AMP-activated protein kinase (AMPK), orchestrates organismal metabolism. However, direct genetic manipulations of the AMPK complex in mice have, so far, produced detrimental phenotypes. Here, as an alternative approach, we alter energy homeostasis by manipulating the upstream nucleotide pool. more...
Organism:
Nothobranchius furzeri
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL26990 GPL33195
68 Samples
Download data: CSV, TXT
Series
Accession:
GSE190757
ID:
200190757

PubMed Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Nothobranchius furzeri)

Organism:
Nothobranchius furzeri
3 Series
54 Samples
Download data
Platform
Accession:
GPL26990
ID:
100026990

3.

Nfr Liver Young WT Full M smp45

Organism:
Nothobranchius furzeri
Source name:
Nfr Liver
Platform:
GPL26990
Series:
GSE190757
Download data
Sample
Accession:
GSM5730988
ID:
305730988

SRA Run Selector

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db=gds|term=GSM5730988[Accession]|query=3|qty=2|blobid=MCID_67317c19f73b361c515053dd|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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